SARS-CoV-2 Spike Protein (B.1.621 - mu) (rho-1D4 tag)

N° du produit ABIN7013133

Détail du produit

Highlights:

• Recombinant trimeric S protein of the SARS-CoV-2 variant of interest B.1.621 mu.
• Contains T95I, Y144S, Y145N, R346K, E484K, N501Y, D614G, P681H and D950N mutations characteristic for the SARS-CoV-2 mu variant (B.1.621).

Antigène: SARS-CoV-2 Spike

Type de proteíne: Recombinant

Attributs du protein: B.1.621 - mu

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Mu

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike protéine est marqué à la rho-1D4 tag.

Application: ELISA, Ligand Binding Assay (LBA)

Fonction: This is the spike protein of the mutant strain B.1.621 (WHO variant of concern Mu).

Specificité: Mutations that differ from "original" SPIKE protein: T95I, Y144S, Y145N, R346K, N501Y, D614G, P681H, D950N

Attributs du produit: All viruses undergo fast mutations to adept quickly to the host's immune response and boost infectivity. SARS-CoV-2, the causative agent of COVID-19, is no exception. Over the course of the COVID-19 pandemic several predominant novel strains have already been identified. The B.1.621 Mu variant was first detected in Colombia in January 2021 and was added to the WHO list of SARS-CoV-2 variants of interest in August 2021.

Purification: affinity chromatography

Pureté: > 98% as determined by SDS-PAGE

Information d'application

Commentaires:

Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence
Size: 1284 amino acids (including Rho1D4 tag and linker) 141903 Da

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG

Stock: -80 °C

Stockage commentaire: Store at -80°C. Avoid freeze-thaw cycles

Détail du antigène

Antigène: SARS-CoV-2 Spike

Autre désignation: SARS2 Spike glycoprotein (SARS-CoV-2 Spike Produits)

Synonymes: E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

UniProt: P0DTC2