KREMEN1 Protein (AA 21-392) (Fc Tag)
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- Antigène Voir toutes KREMEN1 Protéines
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 21-392
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette KREMEN1 protéine est marqué à la Fc Tag.
- Attributs du produit
- Human Kremen-1 protein, Fc Tag
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KREMEN1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Autre désignation
- KREMEN1 (KREMEN1 Produits)
- Synonymes
- KREMEN1 Protein, krm1 Protein, kremen Protein, kremem1 Protein, KREMEN Protein, KRM1 Protein, AV002070 Protein, Kremen Protein, Krm1 Protein, si:ct737139.1 Protein, si:dkeyp-7c9.1 Protein, kringle containing transmembrane protein 1 Protein, kringle containing transmembrane protein 1 S homeolog Protein, KREMEN1 Protein, kremen1 Protein, Kremen1 Protein, kremen1.S Protein
- Sujet
- Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
- Poids moléculaire
- 67.4 kDa
- Pathways
- Signalisation WNT
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