Glucagon Receptor Protein (GCGR) (Fc Tag)
GCGR
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
-
- Antigène Voir toutes Glucagon Receptor (GCGR) Protéines
- Glucagon Receptor (GCGR)
- Type de proteíne
- Recombinant
-
Origine
- Souris
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Glucagon Receptor protéine est marqué à la Fc Tag.
- Fonction
- Mouse GCGR / Glucagon receptor Protein, Fc Tag
- Séquence
- Ala 27 - Lys 137
- Attributs du produit
- Mouse GCGR, Fc Tag (GCR-M5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Lys 137 (Accession # Q61606-1).
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GCGR Protéine
-
Glucagon Receptor (GCGR) (AA 26-136) protein (His tag)
GCGR Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
-
- Indications d'application
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Stock
- -20 °C
- Stockage commentaire
- -20°C
-
- Antigène
- Glucagon Receptor (GCGR)
- Autre désignation
- GCGR / Glucagon receptor (GCGR Produits)
- Synonymes
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Sujet
-
Synonyms: Glucagon R, GCGR,Glucagon receptor,
Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. - Poids moléculaire
- 39.5 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
-
Vous êtes ici:
