ANTXR1 Protein (His tag)

N° du produit ABIN7092772

Détail du produit

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ANTXR1 protéine est marqué à la His tag.

Fonction: Recombinant human ANTXR1 protein with C-terminal 6xHis tag

Specificité: ANTXR1 (Glu33-Ser321) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Autre désignation: ANTXR1 (ANTXR1 Produits)

Synonymes: ANTXR1 Protein, ATR Protein, TEM8 Protein, 2310008J16Rik Protein, 2810405N18Rik Protein, Antrx1 Protein, Tem8 Protein, anthrax toxin receptor 1 Protein, ANTXR1 Protein, Antxr1 Protein

Sujet: Synonymes: ATR
Description: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Poids moléculaire: predicted molecular mass of 33.2 kDa after removal of the signal peptide. The apparent molecular mass of ANTXR1-His is 35-55 kDa due to glycosylation.

UniProt: Q9H6X2