GLUT4 Protein (Fc Tag)

N° du produit ABIN7092815

Détail du produit

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GLUT4 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human SLC2A4 with C-terminal human Fc tag

Specificité: SLC2A4 (Asn46-Thr78) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Autre désignation: SLC2A4 (SLC2A4 Produits)

Synonymes: GLUT4 Protein, Glut-4 Protein, Glut4 Protein, glut4 Protein, slc2a4 Protein, SLC2A4 Protein, solute carrier family 2 member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog Protein, SLC2A4 Protein, Slc2a4 Protein, GLUT4 Protein, slc2a4.L Protein

Sujet: Synonymes: GLUT4
Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of SLC2A4-hFc is 35-55 kDa due to glycosylation.

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg