GLUT4 Protéine

N° du produit ABIN7491733

Détail du produit

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human SLC2A4 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Autre désignation: SLC2A4 (SLC2A4 Produits)

Synonymes: GLUT4 Protein, Glut-4 Protein, Glut4 Protein, glut4 Protein, slc2a4 Protein, SLC2A4 Protein, solute carrier family 2 member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog Protein, SLC2A4 Protein, Slc2a4 Protein, GLUT4 Protein, slc2a4.L Protein

Sujet: GLUT4
Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length SLC2A4 protein has a MW of 54.6 kDa

UniProt: P14672

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg