HBEGF Protein (His tag)
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- Antigène Voir toutes HBEGF Protéines
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette HBEGF protéine est marqué à la His tag.
- Fonction
- Recombinant mouse HBEGF (24-160) protein with C-terminal 6xHis tag
- Specificité
- Mouse HBEGF (24-160) (Gln24-Thr160) 6xHis tag
- Attributs du produit
- Extracellular Domain Protein
- Purification
- affinity purification
- Pureté
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product HBEGF Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- Autre désignation
- HBEGF (HBEGF Produits)
- Synonymes
- hbegf Protein, zgc:165443 Protein, HBEGF Protein, zgc:175091 Protein, DTR Protein, DTS Protein, DTSF Protein, HEGFL Protein, Dtr Protein, GFHB Protein, Hb-egf Protein, Hegfl Protein, AW047313 Protein, Dts Protein, HB-EGF Protein, heparin-binding EGF-like growth factor b Protein, heparin binding EGF like growth factor Protein, Heparin-binding EGF-like growth factor Protein, heparin-binding EGF-like growth factor a Protein, heparin-binding EGF-like growth factor Protein, hbegfb Protein, HBEGF Protein, hbegf Protein, hbegfa Protein, Hbegf Protein
- Sujet
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Synonymes: AW047313, Dtr, Dts, Hegfl
Description: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function] - Poids moléculaire
- predicted molecular mass of 16.0 kDa after removal of the signal peptide.The apparent molecular mass of mHBEGF(24-160)-His is 25-35 kDa due to glycosylation.
- UniProt
- Q06186
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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