ADCYAP1R1 Protein (Fc Tag)

N° du produit ABIN7317286

Détail du produit

Antigène: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ADCYAP1R1 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human ADCYAP1R1 Protein (Fc Tag)

Séquence: Met 1-Ala 155

Attributs du produit: A DNA sequence encoding the human ADCYAP1R1 (P41586) extracellular domain (Met 1-Ala 155) was fused with the Fc region of human IgG1 at the C-terminus.

Pureté: > 88 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Autre désignation: ADCYAP1R1 (ADCYAP1R1 Produits)

Synonymes: PAC1 Protein, PAC1R Protein, PACAPR Protein, PACAPRI Protein, 2900024I10Rik Protein, AI846590 Protein, PACAP1-R Protein, pac1 Protein, pacapr Protein, pacapri Protein, PAC1-R Protein, PACAP-R1 Protein, PACAP-R1A Protein, PACAPR1 Protein, PACAPR1A Protein, adcyap1r1 Protein, adcyap1r1-A Protein, ADCYAP1R1 Protein, ADCYAP receptor type I Protein, adenylate cyclase activating polypeptide 1 receptor 1 Protein, adenylate cyclase activating polypeptide 1 (pituitary) receptor type I Protein, ADCYAP receptor type 1 Protein, adenylate cyclase activating polypeptide 1a (pituitary) receptor type I Protein, adenylate cyclase activating polypeptide 1 (pituitary) receptor type I S homeolog Protein, ADCYAP1R1 Protein, Adcyap1r1 Protein, adcyap1r1 Protein, adcyap1r1a Protein, adcyap1r1.S Protein

Sujet:

Background: SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be secreted in plasma by cancerous cells but at a low level. SERPINB3 significantly attenuates apoptosis by contrasting cytochrome c release from the mitochondria and by antichemotactic effect for NK cells. It may act as a protease inhibitor to modulate the host immune response against tumor cells and may be involved in the malignant behavior of squamous cell carcinoma cells.

Synonym: PAC1,PAC1R,PACAPR,PACAPRI

Poids moléculaire: 42 kDa

UniProt: P41586

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process