BLK Protein (His tag)
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- Antigène Voir toutes BLK Protéines
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BLK protéine est marqué à la His tag.
- Fonction
- Recombinant Human BLK Protein (His Tag)
- Séquence
- Gly2-Pro505
- Attributs du produit
- Recombinant Human Tyrosine-Protein Kinase BLK is produced by our E.coli expression system and the target gene encoding Gly2-Pro505 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 85 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BLK Protéine
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B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) (Active) protein (His-GST)
BLK Origine: Humain Hôte: Insect cells (Sf9) Recombinant SDS, Func Active
B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) protein (GST tag)BLK Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) protein (GST tag)BLK Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) protein (His tag)BLK Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
B Lymphoid Tyrosine Kinase (BLK) (Active) protein (GST tag)BLK Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
B Lymphoid Tyrosine Kinase (BLK) (AA 2-505) protein (His tag)Crystallography grade BLK Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
B Lymphoid Tyrosine Kinase (BLK) (AA 2-499) protein (His tag)Crystallography grade BLK Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 1 mM DTT, pH 7.4.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- Autre désignation
- BLK (BLK Produits)
- Synonymes
- bltk Protein, si:dkey-33i22.2 Protein, zgc:136231 Protein, MODY11 Protein, BLK proto-oncogene, Src family tyrosine kinase Protein, B lymphoid kinase Protein, blk Protein, BLK Protein, Blk Protein
- Sujet
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Background: Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
Synonym: Tyrosine-Protein Kinase Blk, B Lymphocyte Kinase, p55-Blk, BLK,MODY11
- Poids moléculaire
- 58.7 kDa
- NCBI Accession
- NP_001706
- Pathways
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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