BMPR1B Protein (Fc Tag)

N° du produit ABIN7194418

Détail du produit

Antigène: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette BMPR1B protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse BMPR1B/ALK-6 Protein (Fc Tag)

Séquence: Lys14-Lys126

Attributs du produit: A DNA sequence encoding the mouse Bmpr1b (NP_031586.1) (Lys14-Lys126) was expressed with the Fc region of human IgG1 at the C-terminus.

Pureté: > (88.3+9.9) % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Autre désignation: BMPR1B/ALK-6 (BMPR1B Produits)

Synonymes: ALK6 Protein, BMPR-IB Protein, FecB Protein, alk-6 Protein, alk6 Protein, cdw293 Protein, alk6b Protein, zgc:172219 Protein, BMPR1B Protein, AI385617 Protein, ALK-6 Protein, AV355320 Protein, Acvrlk6 Protein, Alk6 Protein, BMPR-1B Protein, CFK-43a Protein, SKR6 Protein, BR1b Protein, alk6tr Protein, bmpr1b Protein, zALK-6 Protein, zgc:92220 Protein, CDw293 Protein, BMP15 Protein, BMPRIB Protein, RPK-1 Protein, bone morphogenetic protein receptor type 1B Protein, bone morphogenetic protein receptor, type IBb Protein, bone morphogenetic protein receptor, type 1B Protein, bone morphogenetic protein receptor, type IBa Protein, BMPR1B Protein, bmpr1b Protein, bmpr1bb Protein, Bmpr1b Protein, bmpr1ba Protein

Sujet:

Background: BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective trasducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.

Synonym: Acvrlk6,AI385617,ALK-6,Alk6,AV355320,BMPR-1B,BMPR-IB,CFK-43a,SKR6

Poids moléculaire: 39.4 kDa

NCBI Accession: NP_031586