EPH Receptor A3 Protein (EPHA3) (His tag)

N° du produit ABIN7195524

Détail du produit

Antigène: EPH Receptor A3 (EPHA3)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: Cette EPH Receptor A3 protéine est marqué à la His tag.

Fonction: Recombinant Rat EphA3 Protein (His Tag)(Active)

Séquence: Met1-His541

Attributs du produit: A DNA sequence encoding the rat EPHA3 (EDL75897.1) (Met1-His541) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 90 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method

Biological Activity Comment: Measured by its binding ability in a functional ELISA.Immobilized rat EPHA3-His at 10 μg/ml (100 μl /well) can bind rat EFNA5-Fc, The EC50 of ratEFNA5-Fc is 9-20ng/ml.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: EPH Receptor A3 (EPHA3)

Autre désignation: EphA3 (EPHA3 Produits)

Synonymes: EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein

Sujet:

Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Synonym: EPHA3

Poids moléculaire: 61.2 kDa

Pathways: Signalisation RTK, Regulation of Cell Size