EPH Receptor A3 Protein (EPHA3) (AA 21-541) (His tag)

N° du produit ABIN7274557

Détail du produit

Antigène: EPH Receptor A3 (EPHA3)

Type de proteíne: Recombinant

Attributs du protein: AA 21-541

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EPH Receptor A3 protéine est marqué à la His tag.

Fonction: Human EPHA3 Protein

Séquence: Glu21-Gln541

Attributs du produit: Recombinant Human EPHA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Gln541.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: EPH Receptor A3 (EPHA3)

Autre désignation: EPHA3 (EPHA3 Produits)

Synonymes: EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein

Sujet: Erythropoietin-producing hepatocellular carcinoma cell surface type-A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (-295~-261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.

Poids moléculaire: 59.9 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.

Pathways: Signalisation RTK, Regulation of Cell Size