Growth Hormone Receptor Protein (GHR) (Fc Tag)

N° du produit ABIN7320745

Détail du produit

Antigène: Growth Hormone Receptor (GHR)

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette Growth Hormone Receptor protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse Growth Hormone Receptor/GHR Protein (Fc Tag)

Séquence: Met1-Gln273

Attributs du produit: Recombinant Mouse Growth Hormone receptor is produced by our Mammalian expression system and the target gene encoding Met1-Gln273 is expressed with a Fc tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Growth Hormone Receptor (GHR)

Autre désignation: Growth Hormone Receptor/GHR (GHR Produits)

Synonymes: GHBP Protein, AA986417 Protein, GHR/BP Protein, GHR Protein, ghr Protein, ghr.a Protein, zgc:162141 Protein, growth hormone receptor Protein, growth hormone receptor L homeolog Protein, growth hormone receptor a Protein, GHR Protein, Ghr Protein, ghr.L Protein, ghr Protein, ghra Protein

Sujet:

Background: Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

Synonym: growth hormone binding protein, growth hormone receptor, serum binding protein, Somatotropin receptor,GHR, GH receptor, GHBP

Poids moléculaire: 58.3 kDa

UniProt: Q3UP14

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Response to Growth Hormone Stimulus