PRKAR1A Protein (His tag)

N° du produit ABIN7318228

Détail du produit

Antigène: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette PRKAR1A protéine est marqué à la His tag.

Fonction: Recombinant Human PRKAR1A Protein (His Tag)

Séquence: Glu2-Val381

Attributs du produit: Recombinant Human cAMP-dependent protein kinase regulatory type I-alpha is produced by our Mammalian expression system and the target gene encoding Glu2-Val381 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Autre désignation: PRKAR1A (PRKAR1A Produits)

Synonymes: ACRDYS1 Protein, ADOHR Protein, CAR Protein, CNC Protein, CNC1 Protein, PKR1 Protein, PPNAD1 Protein, PRKAR1 Protein, TSE1 Protein, 1300018C22Rik Protein, RIalpha Protein, Tse-1 Protein, Tse1 Protein, RIIA Protein, prkar1a Protein, zgc:92515 Protein, im:7047729 Protein, cnc1 Protein, pkr1 Protein, ppnad1 Protein, prkar1 Protein, tse1 Protein, protein kinase cAMP-dependent type I regulatory subunit alpha Protein, protein kinase, cAMP dependent regulatory, type I, alpha Protein, protein kinase cAMP-dependent type 1 regulatory subunit alpha Protein, protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a Protein, cAMP-dependent protein kinase type I-alpha regulatory subunit pseudogene Protein, protein kinase cAMP-dependent type I regulatory subunit alpha S homeolog Protein, PRKAR1A Protein, Prkar1a Protein, prkar1aa Protein, LOC707275 Protein, prkar1a.S Protein

Sujet:

Background: cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.

Synonym: Tissue-specific extinguisher 1,TSE1

Poids moléculaire: 44.0 kDa

UniProt: P10644

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma