PRKG1 Protein (His tag)
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- Antigène Voir toutes PRKG1 Protéines
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette PRKG1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human PRKG1 Protein (His Tag)
- Séquence
- Gly2-Pro686
- Attributs du produit
- Recombinant Human cGMP-Dependent Protein Kinase 1 is produced by our Mammalian expression system and the target gene encoding Gly2-Pro686 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 80 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRKG1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF,20 % glycerol, pH 8.0.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
- Autre désignation
- PRKG1 (PRKG1 Produits)
- Synonymes
- prkg1 Protein, zgc:63955 Protein, Pkgi Protein, cGk1 Protein, 1 Protein, PKG Protein, PRKG1B Protein, PRKGR1B Protein, cGK Protein, cGK 1 Protein, cGK1 Protein, cGKI Protein, cGKI-BETA Protein, cGKI-alpha Protein, CGKI Protein, cGKI-beta Protein, AW125416 Protein, Gm19690 Protein, Prkg1b Protein, Prkgr1b Protein, Prkg1beta Protein, protein kinase, cGMP-dependent, type Ia Protein, protein kinase, cGMP-dependent, type I Protein, protein kinase, cGMP-dependent, type 1 Protein, prkg1a Protein, PRKG1 Protein, prkg1 Protein, Prkg1 Protein
- Sujet
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Background: cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO)/cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-signaling pathway, and other processes involved in several aspects of the CNS like axon guidance, hippocampal and cerebellar learning, circadian rhythm, and nociception.
Synonym: cGMP-Dependent Protein Kinase 1, cGK 1, cGK1, cGMP-Dependent Protein Kinase I, cGKI, PRKG1, PRKG1B, PRKGR1A, PRKGR1B
- Poids moléculaire
- 78.8 kDa
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