RHEB Protein (His tag)

N° du produit ABIN7197635

Détail du produit

Antigène: RHEB (Ras Homolog Enriched in Brain (RHEB))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette RHEB protéine est marqué à la His tag.

Fonction: Recombinant Human RHEB Protein (His Tag)

Séquence: Met 1-Cys181

Attributs du produit: A DNA sequence encoding the human RHEB (Q15382)(Met1-Cys181) was fused with a polyhistide tag at the N-terminus.

Pureté: > 85 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: RHEB (Ras Homolog Enriched in Brain (RHEB))

Autre désignation: RHEB (RHEB Produits)

Synonymes: RHEB2 Protein, RHEB Protein, rheb2 Protein, CG1081 Protein, DReb Protein, Dm Rheb Protein, DmRheb Protein, Dmel\CG1081 Protein, Q9VND8 Protein, RheB Protein, dRheb Protein, rheb Protein, Ras homolog, mTORC1 binding Protein, Ras homolog enriched in brain Protein, ras homolog enriched in brain Protein, Ras homolog, mTORC1 binding L homeolog Protein, RHEB Protein, Rheb Protein, rheb Protein, rheb.L Protein

Sujet:

Background: RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of RHEB is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Synonym: GTP-Binding Protein Rheb, Ras Homolog Enriched in Brain, RHEB, RHEB2

Poids moléculaire: 22.4 kDa

UniProt: Q15382

Pathways: Signalisation RTK