SEMA4D/CD100 Protein (Fc Tag)

N° du produit ABIN7319006

Détail du produit

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette SEMA4D/CD100 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Semaphorin 4D/SEMA4D Protein (Fc Tag)(Active)

Séquence: Met22-Arg734

Attributs du produit: Recombinant Human Semaphorin 4D is produced by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a Fc tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Mouse PLXDC2 -His(Cat: PKSH032037) at 2μg/ml(100 μl/well) can bind Human SEMA4D-Fc.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Autre désignation: Semaphorin 4D/SEMA4D (SEMA4D Produits)

Synonymes: C9orf164 Protein, CD100 Protein, M-sema-G Protein, SEMAJ Protein, coll-4 Protein, Semacl2 Protein, Semaj Protein, Semcl2 Protein, COLL-4 Protein, semaphorin 4D Protein, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Protein, Sema4d Protein, SEMA4D Protein

Sujet:

Background: Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system, Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

Synonym: Semaphorin-4D, A8,BB18, GR3, CD100,C9orf164,CD100,coll-4,M-sema-G,SEMAJ

Poids moléculaire: 106.4 kDa

UniProt: Q92854

Pathways: Regulation of Cell Size