SIRPG Protein (Fc Tag)

N° du produit ABIN7319304

Détail du produit

Antigène: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette SIRPG protéine est marqué à la Fc Tag.

Fonction: Recombinant Human SIRP gamma/CD172g Protein (Fc Tag)

Séquence: Glu29-Pro360

Attributs du produit: Recombinant Human Signal-Regulatory Protein gamma is produced by our Mammalian expression system and the target gene encoding Glu29-Pro360 is expressed with a Fc tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Autre désignation: SIRP gamma/CD172g (SIRPG Produits)

Synonymes: CD172g Protein, SIRP-B2 Protein, SIRPB2 Protein, SIRPgamma Protein, bA77C3.1 Protein, SIRPG Protein, signal regulatory protein gamma Protein, signal-regulatory protein gamma Protein, SIRPG Protein, LOC716034 Protein, LOC102138723 Protein

Sujet:

Background: Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.

Synonym: Signal-Regulatory Protein Gamma, SIRP-Gamma, CD172 Antigen-Like Family Member B, Signal-Fegulatory Protein Beta-2, SIRP-b2, SIRP-Beta-2, CD172g, SIRPG, SIRPB2

Poids moléculaire: 63.9 kDa

UniProt: Q9P1W8