SIRPG Protein (AA 29-360) (His-Avi Tag,Biotin)

N° du produit ABIN7275659

Détail du produit

Antigène: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Type de proteíne: Recombinant

Attributs du protein: AA 29-360

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SIRPG protéine est marqué à la His-Avi Tag,Biotin.

Fonction: Biotinylated Human SIRP gamma/CD172g Protein

Séquence: Glu29-Pro360

Attributs du produit: Recombinant Biotinylated Human SIRP gamma/CD172g Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu29-Pro360.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-SIRP alpha Antibody, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human SIRP gamma, His Tag with the EC50 of 35.5ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Autre désignation: SIRP gamma (SIRPG Produits)

Synonymes: CD172g Protein, SIRP-B2 Protein, SIRPB2 Protein, SIRPgamma Protein, bA77C3.1 Protein, SIRPG Protein, signal regulatory protein gamma Protein, signal-regulatory protein gamma Protein, SIRPG Protein, LOC716034 Protein, LOC102138723 Protein

Sujet: Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

Poids moléculaire: 39.7 kDa. Due to glycosylation, the protein migrates to 48-53 kDa based on Tris-Bis PAGE result.

UniProt: Q9P1W8