EPH Receptor B1 Protein (EPHB1) (Fc Tag)

N° du produit ABIN7319920

Détail du produit

Antigène: EPH Receptor B1 (EPHB1)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette EPH Receptor B1 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Ephrin B Receptor 1/EphB1 (C-Fc)

Séquence: Met18-Pro540

Attributs du produit: Recombinant Human Ephrin Type-B Receptor 1 is produced by our Mammalian expression system and the target gene encoding Met18-Pro540 is expressed with a Fc tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Commentaires:

85-100 kDa

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: EPH Receptor B1 (EPHB1)

Autre désignation: EphB1 (EPHB1 Produits)

Synonymes: ELK Protein, EPHT2 Protein, Hek6 Protein, NET Protein, ephb1-a Protein, xek Protein, Xek Protein, MGC89790 Protein, EPHB1 Protein, CEK6 Protein, EK6 Protein, 9330129L11 Protein, AW488255 Protein, C130099E04Rik Protein, Cek6 Protein, ENSMUSG00000074119 Protein, Elk Protein, Elkh Protein, Net Protein, Ephb2 Protein, Erk Protein, elk Protein, EPH receptor B1 Protein, EPH receptor B1 S homeolog Protein, ephrin type-B receptor 1 Protein, Eph receptor B1 Protein, EPHB1 Protein, ephb1.S Protein, ephb1 Protein, LOC100467687 Protein, Ephb1 Protein

Sujet:

Background: Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

Synonym: Ephrin Type-B Receptor 1, ELK, EPH Tyrosine Kinase 2, EPH-Like Kinase 6, EK6, hEK6, Neuronally-Expressed EPH, Related Tyrosine Kinase, NET, Tyrosine-Protein Kinase Receptor EPH-2, EPHB1, ELK, EPHT2, HEK6

Poids moléculaire: 85.6 kDa

UniProt: P54762

Pathways: Signalisation RTK