SARS-CoV Spike (SARS-CoV S)
(SARS-Coronavirus Spike Protein (SARS-CoV S))
Type de proteíne
Recombinant
Attributs du protein
R667A, Trimer
Origine
SARS Coronavirus GD01
Source
HEK-293 Cells
Purification/Conjugué
Cette SARS-CoV Spike protéine est marqué à la His tag.
Fonction
SARS-CoV GD01 Spike Trimer (R667A, KV968-969PP), His Tag (MALS verified)
Séquence
Ser 14 - Pro 1195
Attributs du produit
SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP).
SARS-CoV S
Origine: SARS Coronavirus (SARS-CoV)
Hôte: Escherichia coli (E. coli)
Recombinant
>90 %
ELISA
Indications d'application
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
PBS
Stock
-20 °C
Stockage commentaire
-20°C
Antigène
SARS-CoV Spike (SARS-CoV S)
(SARS-Coronavirus Spike Protein (SARS-CoV S))
Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.