ApoE3 Protein (AA 19-317) (His tag,Biotin)
ApoE3
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
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- Antigène Tous les produits ApoE3
- ApoE3 (Apolipoprotein E3 (ApoE3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-317
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ApoE3 protéine est marqué à la His tag,Biotin.
- Fonction
- Biotinylated Human APOE3/Apolipoprotein E Protein (Primary Amine Labeling)
- Séquence
- Lys19-His317
- Attributs du produit
- Recombinant Biotinylated Human APOE3/Apolipoprotein E Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus.It contains Lys19-His317.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.41 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Apolipoprotein E3 (ApoE3) (AA 19-317) protein (His tag)
ApoE3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ApoE3 (Apolipoprotein E3 (ApoE3))
- Autre désignation
- APOE3 (ApoE3 Produits)
- Synonymes
- AD2 Protein, LDLCQ5 Protein, LPG Protein, apolipoprotein E Protein, APOE Protein
- Sujet
- Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
- Poids moléculaire
- 35.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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