PTK7 Protein (AA 39-712) (His tag)

N° du produit ABIN7274039

Détail du produit

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Type de proteíne: Recombinant

Attributs du protein: AA 39-712

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette PTK7 protéine est marqué à la His tag.

Fonction: Cynomolgus PTK7/CCK4 Protein

Séquence: Ala39-Thr712

Attributs du produit: Recombinant Cynomolgus PTK7/CCK4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala39-Thr712.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Autre désignation: PTK7 (PTK7 Produits)

Synonymes: PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein

Sujet: Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.

Poids moléculaire: 75.73 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5VNI5

Pathways: Signalisation RTK, Tube Formation