EPH Receptor B3 Protein (EPHB3) (AA 34-559) (His tag)

N° du produit ABIN7274559

Détail du produit

Antigène: EPH Receptor B3 (EPHB3)

Type de proteíne: Recombinant

Attributs du protein: AA 34-559

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EPH Receptor B3 protéine est marqué à la His tag.

Fonction: Human EphB3 Protein

Séquence: Gly34-Leu559

Attributs du produit: Recombinant Human EphB3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly34-Leu559.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: EPH Receptor B3 (EPHB3)

Autre désignation: EphB3 (EPHB3 Produits)

Synonymes: tck Protein, MGC83457 Protein, EPHB3 Protein, ETK2 Protein, HEK2 Protein, TYRO6 Protein, AW456895 Protein, Cek10 Protein, Etk2 Protein, MDK5 Protein, Sek4 Protein, Tyro6 Protein, CEK10 Protein, EK10 Protein, ek3 Protein, ephb3 Protein, fc62d03 Protein, rtk3 Protein, wu:fc62d03 Protein, zek3 Protein, EPH receptor B3 Protein, EPH receptor B3 L homeolog Protein, Eph receptor B3 Protein, eph receptor B3a Protein, Eph receptor tyrosine kinase Protein, EPHB3 Protein, ephb3.L Protein, ephb3 Protein, Ephb3 Protein, ephb3a Protein

Sujet: Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.

Poids moléculaire: 58.6 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.

UniProt: P54753

Pathways: Signalisation RTK