FAP Protein (AA 26-760) (His-Avi Tag,Biotin)

N° du produit ABIN7274582

Détail du produit

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Type de proteíne: Recombinant

Attributs du protein: AA 26-760

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette FAP protéine est marqué à la His-Avi Tag,Biotin.

Fonction: Biotinylated Cynomolgus FAP Protein

Séquence: Leu26-Asp760

Attributs du produit: Recombinant Biotinylated Cynomolgus FAP Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu26-Asp760.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-FAP Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus FAP, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 200 mM Arginine ( pH 8.2).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Autre désignation: FAP (FAP Produits)

Synonymes: fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein

Sujet: Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.

Poids moléculaire: 88 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_005573377

Pathways: Tube Formation