GPC2 Protein (AA 22-556) (His tag)

N° du produit ABIN7274777

Détail du produit

Antigène: GPC2 (Glypican 2 (GPC2))

Type de proteíne: Recombinant

Attributs du protein: AA 22-556

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette GPC2 protéine est marqué à la His tag.

Fonction: Mouse Glypican 2/GPC2 Protein

Séquence: His22-Ser556

Attributs du produit: Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: GPC2 (Glypican 2 (GPC2))

Autre désignation: Glypican 2 (GPC2 Produits)

Synonymes: 2410016G05Rik Protein, glypican 2 Protein, glypican 2 (cerebroglycan) Protein, GPC2 Protein, Gpc2 Protein

Sujet: Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.

Poids moléculaire: 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Tris-Bis PAGE result.

UniProt: Q8BKV1

Pathways: Glycosaminoglycan Metabolic Process