GPC2 Protein (AA 22-556) (His tag)
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- Antigène Voir toutes GPC2 Protéines
- GPC2 (Glypican 2 (GPC2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-556
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette GPC2 protéine est marqué à la His tag.
- Fonction
- Mouse Glypican 2/GPC2 Protein
- Séquence
- His22-Ser556
- Attributs du produit
- Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GPC2 (Glypican 2 (GPC2))
- Autre désignation
- Glypican 2 (GPC2 Produits)
- Synonymes
- 2410016G05Rik Protein, glypican 2 Protein, glypican 2 (cerebroglycan) Protein, GPC2 Protein, Gpc2 Protein
- Sujet
- Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
- Poids moléculaire
- 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8BKV1
- Pathways
- Glycosaminoglycan Metabolic Process
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