Hemopexin Protein (HPX) (AA 24-462) (His tag)

N° du produit ABIN7274827

Détail du produit

Antigène: Hemopexin (HPX)

Type de proteíne: Recombinant

Attributs du protein: AA 24-462

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Hemopexin protéine est marqué à la His tag.

Fonction: Human HPX Protein

Séquence: Thr24-His462

Attributs du produit: Recombinant Human HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr24-His462.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Hemopexin (HPX)

Autre désignation: HPX (HPX Produits)

Synonymes: HPX Protein, HX Protein, Hpxn Protein, hx Protein, wu:fi17f11 Protein, wu:fi19a10 Protein, hemopexin Protein, HPX Protein, Mmar10_1124 Protein, Hpx Protein, hpx Protein

Sujet: Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.

Poids moléculaire: 50.3 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.

UniProt: P02790

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response