IL3RA Protein (AA 19-305) (Fc Tag)
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- Antigène Voir toutes IL3RA Protéines
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-305
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL3RA protéine est marqué à la Fc Tag.
- Fonction
- Human IL-3 R alpha/CD123 Protein
- Séquence
- Thr19-Arg305
- Attributs du produit
- Recombinant Human IL-3 R alpha/CD123 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr19-Arg305.
- Pureté
- > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-3, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-3 R alpha, hFc Tag with the EC50 of 42.7ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Autre désignation
- IL-3 R alpha (IL3RA Produits)
- Synonymes
- CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
- Sujet
- Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
- Poids moléculaire
- 59.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- Signalistation JAK/STAT
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