IL-5 Protein (AA 21-133) (His-Avi Tag)
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- Antigène Voir toutes IL-5 (IL5) Protéines
- IL-5 (IL5) (Interleukin 5 (IL5))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 21-133
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL-5 protéine est marqué à la His-Avi Tag.
- Fonction
- Mouse IL-5 Protein
- Séquence
- Met21-Gly133
- Attributs du produit
- Recombinant Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Met21-Gly133.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.495 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL5 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 7.0).
- Stock
- -80 °C
- Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL-5 (IL5) (Interleukin 5 (IL5))
- Autre désignation
- IL-5 (IL5 Produits)
- Synonymes
- EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
- Sujet
- IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).
- Poids moléculaire
- 16.03 kDa. Due to glycosylation, the protein migrates to 16.03 kDa and 20-32 kDa based on Tris-Bis PAGE result.
- UniProt
- P04401
- Pathways
- Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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