ILDR2 Protein (AA 21-184) (Fc Tag)

N° du produit ABIN7274999

Détail du produit

Antigène: ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))

Type de proteíne: Recombinant

Attributs du protein: AA 21-184

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ILDR2 protéine est marqué à la Fc Tag.

Fonction: Human ILDR2 Protein

Séquence: Leu21-Met184

Attributs du produit: Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))

Autre désignation: ILDR2 (ILDR2 Produits)

Synonymes: C1orf32 Protein, RP4-782G3.2 Protein, dJ782G3.1 Protein, immunoglobulin like domain containing receptor 2 Protein, ILDR2 Protein

Sujet: Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.

Poids moléculaire: 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.

UniProt: Q71H61