Klotho beta Protein (KLB) (AA 53-994) (His tag)
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- Antigène Voir toutes Klotho beta (KLB) Protéines
- Klotho beta (KLB)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 53-994
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Klotho beta protéine est marqué à la His tag.
- Fonction
- Mouse Beta Klotho Protein
- Séquence
- Phe53-Pro994
- Attributs du produit
- Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.
- Pureté
- > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product KLB Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Stock
- -80 °C
- Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Klotho beta (KLB)
- Autre désignation
- Beta Klotho (KLB Produits)
- Synonymes
- KLB Protein, BKL Protein, AV071179 Protein, betaKlotho Protein, Klb-ps1 Protein, RGD1308227 Protein, klotho beta Protein, KLB Protein, Klb Protein
- Sujet
- Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
- Poids moléculaire
- 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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