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Klotho beta Protein (KLB) (AA 53-994) (His tag)

KLB Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
N° du produit ABIN7275093
  • Antigène Voir toutes Klotho beta (KLB) Protéines
    Klotho beta (KLB)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 53-994
    Origine
    • 5
    • 4
    • 1
    • 1
    Souris
    Source
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette Klotho beta protéine est marqué à la His tag.
    Fonction
    Mouse Beta Klotho Protein
    Séquence
    Phe53-Pro994
    Attributs du produit
    Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.
    Pureté
    > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product KLB Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Klotho beta (KLB)
    Autre désignation
    Beta Klotho (KLB Produits)
    Synonymes
    KLB Protein, BKL Protein, AV071179 Protein, betaKlotho Protein, Klb-ps1 Protein, RGD1308227 Protein, klotho beta Protein, KLB Protein, Klb Protein
    Sujet
    Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
    Poids moléculaire
    109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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