MCAM Protein (AA 24-563) (His tag)

N° du produit ABIN7275301

Détail du produit

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Type de proteíne: Recombinant

Attributs du protein: AA 24-563

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette MCAM protéine est marqué à la His tag.

Fonction: Mouse MUC18/CD146 Protein

Séquence: Val24-Val563

Attributs du produit: Recombinant Mouse MUC18/CD146 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val24-Val563.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: MUC18 (MCAM Produits)

Synonymes: CD146 Protein, MUC18 Protein, Muc18 Protein, 1-gicerin Protein, AV025631 Protein, CD149 Protein, s-endo Protein, s-gicerin Protein, cd146 Protein, gicerin Protein, id:ibd3512 Protein, mcam Protein, MCAM Protein, melanoma cell adhesion molecule Protein, melanoma cell adhesion molecule b Protein, MCAM Protein, Mcam Protein, mcamb Protein

Sujet: METCAM/MUC18 is an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family. It can carry out common functions of CAMs which is to perform intercellular interactions and interaction of cell with extracellular matrix in tumor microenvironment, to interact with various signaling pathways and to regulate general behaviors of cells.The above positive correlation is fortuitous, actually METCAM/MUC18 acts as a tumor and metastasis suppressor for the ovarian carcinoma cells.

Poids moléculaire: 60.9 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.