SARS-CoV NSP3 Protein (AA 1-314) (His-Avi Tag)

N° du produit ABIN7275547

Détail du produit

Antigène: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-314

Origine: SARS Coronavirus (SARS-CoV)

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SARS-CoV NSP3 protéine est marqué à la His-Avi Tag.

Fonction: SARS PLpro/papain-like protease Protein

Séquence: Glu1-Ile314

Attributs du produit: Recombinant SARS-CoV-2 PLpro/papain-like protease Protein is expressed from E.coil with His tag and Avi tag at the N-Terminus.It contains Glu1-Ile314.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 100 mM NaCl, 10 % Glycerol ( pH 7.8).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))

Autre désignation: PLpro (SARS-CoV NSP3 Produits)

Classe de substances: Viral Protein

Sujet: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Poids moléculaire: 38.6 kDa same as Tris-Bis PAGE result.

UniProt: P0C6U8