ITGAV/ITGB6 Protein (Biotin,His-Avi Tag)
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- Antigène Tous les produits ITGAV/ITGB6
- ITGAV/ITGB6 (Integrin AlphaV Beta6 (ITGAV/ITGB6))
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ITGAV/ITGB6 protéine est marqué à la Biotin,His-Avi Tag.
- Fonction
- Biotinylated Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
- Séquence
- Phe 31 - Val 988 & Gly 22 - Pro 708
- Attributs du produit
- Biotinylated Mouse ITGAV&ITGB6 Heterodimer Protein, His,Avitag&Tag Free is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 988 & Gly 22 - Pro 708 (Accession # P43406-1 & Q9Z0T9-1).
- Pureté
- 95,00 %
- niveau d'endotoxine
- 1.0 EU per μg
- Classe de qualité
- MALS verified
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Integrin AlphaV Beta6 (ITGAV/ITGB6) (AA 31-988) protein (His tag)
ITGAV/ITGB6 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV Beta6 (ITGAV/ITGB6) (AA 31-993) protein (His tag)ITGAV/ITGB6 Origine: Macaque rhésus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV Beta6 (ITGAV/ITGB6) (AA 31-992) (Active) protein (His tag)ITGAV/ITGB6 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Integrin AlphaV Beta6 (ITGAV/ITGB6) (AA 31-992) (Active) protein (His tag,AVI tag,Biotin)ITGAV/ITGB6 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
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- Commentaires
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Biotinylated Mouse ITGAV&ITGB6 Heterodimer Protein has a calculated MW of 114.2 kDa (ITGAV) & 80.2 kDa (ITGB6). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB6 contains no tag but a basic tail at the C-terminus.The protein migrates as 80-90 kDa and 135-150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- ITGAV/ITGB6 (Integrin AlphaV Beta6 (ITGAV/ITGB6))
- Autre désignation
- Integrin alpha V beta 6 (ITGAV/ITGB6 Produits)
- Sujet
- Synonyms:Integrin alpha V beta 6,ITGAV&ITGB6,Description:Integrin alpha V beta 6 is a heterodimer of beta-6 associating with alpha-V. Integrin alpha-V beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Also, Integrin alpha-V beta-6 acts as a receptor for coxsackievirus A9 and coxsackievirus B1 as well as herpes simplex virus-1/HHV-1. Furthermore, it binds the TGF-beta latency-associated peptide (LAP) and activates TGF-beta 1 or TGF-beta 3 from large latent complexes. This activation requires interaction with LTBP-1 and fibronectin, and is enhanced by PAR-1.
- Poids moléculaire
- 114.2 kDa | 80.2 kDa
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