GAS6 Protein (AA 28-674) (His tag)

N° du produit ABIN7454127

Détail du produit

Antigène: GAS6 (Growth Arrest-Specific 6 (GAS6))

Type de proteíne: Recombinant

Attributs du protein: AA 28-674

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette GAS6 protéine est marqué à la His tag.

Fonction: Mouse GAS6 Protein

Séquence: Val28-Pro674

Attributs du produit: Recombinant Mouse GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val28-Pro674.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Mouse GAS6, His Tag at 5μg/m l (100μl/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.1ng/ml determined by ELISA (QC Test). The affinity constant of 15.62 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: GAS6 (Growth Arrest-Specific 6 (GAS6))

Autre désignation: GAS6 (GAS6 Produits)

Synonymes: fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein

Sujet: Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).

Poids moléculaire: 73.09 kDa. Due to glycosylation, the protein migrates to 74-90 kDa based on Tris-Bis PAGE result.

UniProt: Q61592

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response