SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (His tag)

N° du produit ABIN7490687

Détail du produit

Antigène: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Type de proteíne: Recombinant

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Nucleocapsid protéine est marqué à la His tag.

Fonction: Recombinant SARS-CoV-2 Nucleocapsid (P13L, E31del, R32del, S33del, R203K, G204R) protein with C-terminal 6xHis tag

Specificité: Nucleocapsid (P13L, E31del, R32del, S33del, R203K, G204R) (Met1-Ala419) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Autre désignation: SARS-CoV-2 N (SARS-CoV-2 N Produits)

Synonymes: nucleocapsid phosphoprotein Protein, N Protein

Classe de substances: Viral Protein

Sujet: Nucleocapsid protein,NP,Protein N,Omicron (B.1.1.529)
Description: Coronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.

Poids moléculaire: predicted molecular mass of 46.3 kDa after removal of the signal peptide. The apparent molecular mass of Nucleocapsid (D63G, R203M, D377Y)-His is 55-70 kDa due to glycosylation.

UniProt: P0DTC9