Prokineticin Receptor 1 Protein (PROKR1) (Fc Tag)

N° du produit ABIN7491275

Détail du produit

Antigène: Prokineticin Receptor 1 (PROKR1)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Prokineticin Receptor 1 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human PROKR1 Protein with C-terminal human Fc tag

Specificité: PROKR1 (Met1-Lys62) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Prokineticin Receptor 1 (PROKR1)

Autre désignation: PROKR1 (PROKR1 Produits)

Synonymes: EG-VEGFR1 Protein, Gpr73 Protein, Pkr1 Protein, GPR73 Protein, GPR73a Protein, PKR1 Protein, ZAQ Protein, PROKR1 Protein, prokineticin receptor 1 Protein, Prokr1 Protein, PROKR1 Protein

Sujet: GPR73, GPR73a, PK-R1, PKR1, ZAQ
Description: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]

Poids moléculaire: predicted molecular mass of 33.1 kDa after removal of the signal peptide. The apparent molecular mass of PROKR1-hFc is 35-70 kDa due to glycosylation.

UniProt: Q8TCW9

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma