Angiopoietin 2 Protein (ANGPT2) (His tag)
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- Antigène Voir toutes Angiopoietin 2 (ANGPT2) Protéines
- Angiopoietin 2 (ANGPT2)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Angiopoietin 2 protéine est marqué à la His tag.
- Fonction
- Recombinant Human ANGPT2 (19-496) Protein with C-terminal 6xHis tag
- Specificité
- ANGPT2 (Tyr19-Phe496) 6xHis tag
- Attributs du produit
- Extracellular Domain Protein
- Pureté
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ANGPT2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- Angiopoietin 2 (ANGPT2)
- Autre désignation
- ANGPT2 (ANGPT2 Produits)
- Synonymes
- AGPT2 Protein, ANG2 Protein, Agpt2 Protein, Ang-2 Protein, Ang2 Protein, ang2 Protein, angpt2 Protein, ANGIOPOIETIN-2 Protein, ANG-2 Protein, ANGPT2 Protein, Angrp Protein, Rnase5b Protein, ANG3 Protein, C11orf2 Protein, C11orf3 Protein, FFR Protein, angiopoietin 2 Protein, angiopoietin 2b Protein, angiogenin, ribonuclease A family, member 2 Protein, VPS51, GARP complex subunit Protein, ANGPT2 Protein, Angpt2 Protein, angpt2b Protein, Ang2 Protein, VPS51 Protein
- Sujet
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AGPT2, ANG2, LMPHM10This gene belongs to the angiopoietin family of growth factors.
Description: The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020] - Poids moléculaire
- predicted molecular mass of 55.7 kDa after removal of the signal peptide. The apparent molecular mass of ANGPT2(19-496)-His is 55-70 kDa due to glycosylation.
- UniProt
- O15123
- Pathways
- Signalisation RTK
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