Prostaglandin D2 Receptor 2 (PTGDR2) Protéine

N° du produit ABIN7491717

Détail du produit

Antigène: Prostaglandin D2 Receptor 2 (PTGDR2)

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human PTGDR2 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: Prostaglandin D2 Receptor 2 (PTGDR2)

Autre désignation: PTGDR2 (PTGDR2 Produits)

Synonymes: CD294 Protein, CRTH2 Protein, DL1R Protein, DP2 Protein, GPR44 Protein, Crth2 Protein, Grp45 Protein, Ptgdr2 Protein, Gpr44 Protein, prostaglandin D2 receptor 2 Protein, PTGDR2 Protein, Ptgdr2 Protein

Sujet: CD294, CRTH2, DL1R, DP2, GPR44
Description: This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]

Poids moléculaire: The human full length PTGDR2 protein has a MW of 43.7 kDa

UniProt: Q9Y5Y4

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling