ACVR2A Protein (AA 20-135) (His tag)

N° du produit ABIN7504221

Détail du produit

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Type de proteíne: Recombinant

Attributs du protein: AA 20-135

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ACVR2A protéine est marqué à la His tag.

Fonction: Human Activin RIIA/ACVR2A Protein

Séquence: Ala20-Pro135

Attributs du produit: Recombinant Human Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala20-Pro135.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Autre désignation: Activin RIIA (ACVR2A Produits)

Synonymes: ACVR2 Protein, ACVR2A Protein, XSTK9 Protein, actrii Protein, acvr2 Protein, ACTRII Protein, Acvr2 Protein, rActR-II Protein, actr2a Protein, acvr2a Protein, wu:fa02e10 Protein, ActrIIa Protein, TactrII Protein, activin A receptor type 2A Protein, activin A receptor type 2A L homeolog Protein, activin A receptor type 2Aa Protein, activin receptor IIA Protein, ACVR2A Protein, acvr2a Protein, Acvr2a Protein, acvr2a.L Protein, acvr2aa Protein

Sujet: Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.

Poids moléculaire: 14.50 kDa. Due to glycosylation, the protein migrates to 30-42 kDa based on Tris-Bis PAGE result.