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DLL4 Protein (AA 27-524) (His tag)

DLL4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
N° du produit ABIN7504312
  • Antigène Voir toutes DLL4 Protéines
    DLL4 (delta-Like 4 (DLL4))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 27-524
    Origine
    • 12
    • 5
    • 3
    Humain
    Source
    • 8
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DLL4 protéine est marqué à la His tag.
    Fonction
    Human DLL4 Protein
    Séquence
    Ser27-Pro524
    Attributs du produit
    Recombinant Human DLL4 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser27-Pro524.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product DLL4 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DLL4 (delta-Like 4 (DLL4))
    Autre désignation
    DLL4 (DLL4 Produits)
    Synonymes
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    Sujet
    Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
    Poids moléculaire
    55.38 kDa. Due to glycosylation, the protein migrates to 56-70 kDa based on Tris-Bis PAGE result.
    Pathways
    Signalisation Notch
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