PKC iota Protein (AA 10-596) (His tag)

N° du produit ABIN7504509

Détail du produit

Antigène: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Type de proteíne: Recombinant

Attributs du protein: AA 10-596

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette PKC iota protéine est marqué à la His tag.

Fonction: Human PKC iota Protein

Séquence: Met10-Val596

Attributs du produit: Recombinant Human PKC iota Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met10-Val596.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in 50 mM Tris, 100 mM NaCl, 0.5 mM GSH, 0.5 mM PMSF, 10 % glycerol ( pH 7.4).

Agent conservateur: PMSF

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))

Autre désignation: PKC iota (PRKCI Produits)

Synonymes: DXS1179E Protein, PKCI Protein, nPKC-iota Protein, aPKC[l] Protein, hal Protein, has Protein, PRKCI Protein, PKC Protein, 2310021H13Rik Protein, AI427505 Protein, PKClambda Protein, Pkci Protein, Pkcl Protein, Prkcl Protein, aPKClambda Protein, mKIAA4165 Protein, protein kinase C iota Protein, protein kinase C, iota Protein, PRKCI Protein, prkci Protein, Prkci Protein

Sujet: PKClambda/iota belongs to the third group of the PKC family, atypical PKC (aPKC), together with PKCzeta based on its sequence divergence from conventional and novel PKCs observed not only in the N-terminal regulatory domain but also in the kinase domain. Although one of the most distinct features of aPKC is its single, unrepeated cysteine-rich domain, recent studies have revealed that the N-terminal regulatory domain has additional aPKC-specific structural motifs involved in various protein-protein interactions, which are important for the regulation and the subcellular targeting of aPKC.

Poids moléculaire: 68.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

UniProt: P41743

Pathways: Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation