Ret Proto-Oncogene Protein (RET) (AA 29-635) (His tag)

N° du produit ABIN7504518

Détail du produit

Antigène: Ret Proto-Oncogene (RET)

Type de proteíne: Recombinant

Attributs du protein: AA 29-635

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Ret Proto-Oncogene protéine est marqué à la His tag.

Fonction: Human RET Protein

Séquence: Leu29-Arg635

Attributs du produit: Recombinant Human RET Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu29-Arg635.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Ret Proto-Oncogene (RET)

Autre désignation: RET (RET Produits)

Synonymes: c-ret Protein, cret Protein, etID315074.13 Protein, ret1 Protein, wu:fd13h01 Protein, X-ret Protein, ret-A Protein, xret Protein, RET Protein, MTC1 Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, RET9 Protein, c-Ret Protein, ret proto-oncogene receptor tyrosine kinase Protein, ret proto-oncogene S homeolog Protein, ret proto-oncogene Protein, ret Protein, ret.S Protein, RET Protein, Ret Protein

Sujet: RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers.

Poids moléculaire: 68.87 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.

Pathways: Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation