E-cadherin Protein (AA 155-375) (His tag)

N° du produit ABIN7504962

Détail du produit

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Type de proteíne: Recombinant

Attributs du protein: AA 155-375

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette E-cadherin protéine est marqué à la His tag.

Séquence: Asp155-Phe375

Attributs du produit: A DNA sequence encoding the Human CDH1 (P12830-1) (Asp155-Phe375) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >85 % as determined by reducing SDS-PAGE.

Information d'application

Commentaires:

used as Immunogen for (ABIN6999858, ABIN7234109, ABIN7234110 and ABIN7234111)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Autre désignation: CDH1 (CDH1 Produits)

Synonymes: Arc-1 Protein, CD324 Protein, CDHE Protein, ECAD Protein, LCAM Protein, UVO Protein, E-cadherin Protein, cdh1 Protein, si:dz180o5.2 Protein, uvo Protein, lcam Protein, E-Cad Protein, XBcad Protein, l-cam Protein, xcdh1 Protein, cdhc-A Protein, xb-cad Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, uvomorulin Protein, XB-cadherin Protein, arc-1 Protein, cd324 Protein, cdhe Protein, ecad Protein, AA960649 Protein, E-cad Protein, Ecad Protein, L-CAM Protein, Um Protein, cadherin 1 Protein, si:busm1-180o5.2 Protein, cadherin 1, type 1, E-cadherin (epithelial) Protein, cadherin 1, type 1 S homeolog Protein, CDH1 Protein, si:busm1-180o5.2 Protein, cdh1 Protein, Cdh1 Protein, cdh1.S Protein

Sujet:

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Synonym: Arc 1,CADH1,Cadherin 1,cadherin 1 type 1 E-cadherin,Cadherin1,CAM 120/80,CD 324,CD324,CD324 antigen,cdh1,CDHE,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,epithelial calcium dependant adhesion protein,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin

Poids moléculaire: 23.9 kDa

Pathways: Signalisation WNT, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation