MYDGF Protein (His tag)

N° du produit ABIN7536442

Détail du produit

Antigène: MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MYDGF protéine est marqué à la His tag.

Fonction: Recombinant Human MYDGF Protein

Séquence: VSEPTTVAFD VRPGGVVHSF SHNVGPGDKY TCMFTYASQG GTNEQWQMSL GTSEDHQHFT CTIWRPQGKS YLYFTQFKAE VRGAEIEYAM AYSKAAFERE SDVPLKTEEF EVTKTAVAHR PGAFKAELSK LVIVAKASRT EL

Specificité: Val32-Leu173

Pureté: > 97 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 1.46 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))

Autre désignation: MYDGF (D17Wsu104e Produits)

Synonymes: EUROIMAGE1875335 Protein, IL25 Protein, IL27 Protein, IL27w Protein, R33729_1 Protein, SF20 Protein, Il25 Protein, Ly6elg Protein, myeloid derived growth factor Protein, MYDGF Protein, Mydgf Protein

Sujet:

Description: Myeloid-Derived Growth Factor, or MYDGF, is a Bone marrow-derived monocyte protein, and it is correlated with enhanced metabolic activity, suppression of apoptosis, and stimulation of cell proliferation . MYDGF is expressed predominantly in inflammatory cells, such as monocytes and macrophages . Up-regulation of MYDGF expression was also found during adipocyte differentiation . Expression of MYDGF was induced in the circulation and heart tissue after myocardial infarction. It promotes cardiac myocyte survival by stimulating endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway, and inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway . MYDGF was found over-expressed in approximately two-thirds of Hepatocellular Carcinoma (HCC) tissues, and its expression was significantly positively correlated with that of alpha-fetoprotein (AFP) .

Name: IL25, IL27, SF20, IL27w, C19orf10, R33729_1, EUROIMAGE1875335,MYDGF

ID gène: 56005

UniProt: Q969H8