EFNA4 Protein (Fc Tag,His tag)

N° du produit ABIN7519950

Détail du produit

Antigène: EFNA4 (Ephrin A4 (EFNA4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EFNA4 protéine est marqué à la Fc Tag,His tag.

Fonction: Active Recombinant Human Ephrin-A4/EFNA4 Protein

Séquence: LRHVVYWNSS NPRLLRGDAV VELGLNDYLD IVCPHYEGPG PPEGPETFAL YMVDWPGYES CQAEGPRAYK RWVCSLPFGH VQFSEKIQRF TPFSLGFEFL PGETYYYISV PTPESSGQCL RLQVSVCCKE RKSESAHPVG SPGESG

Specificité: Leu26-Gly171

Pureté: > 80 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human EphA7 at 0.5 μg/mL (100 μL/well) can bind Human EFNA4 with a linear range of 0.039-0.942 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: EFNA4 (Ephrin A4 (EFNA4))

Autre désignation: Ephrin-A4/EFNA4 (EFNA4 Produits)

Synonymes: EFNA4 Protein, EFL-4 Protein, Epl4 Protein, LERK-4 Protein, EFL4 Protein, EPLG4 Protein, LERK4 Protein, ephrin A4 Protein, ephrin-A4 L homeolog Protein, ephrin-A4 Protein, EFNA4 Protein, efna4.L Protein, efna4 Protein, Efna4 Protein

Sujet:

Description: EPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A4/EFNA4 functions as a cell surface GPI-bound ligand for Eph receptor, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.

Name: EFL4,EPLG4,LERK4,EFNA4

ID gène: 1945

UniProt: P52798

Pathways: Signalisation RTK