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Ephrin A5 Protein (EFNA5) (Fc Tag,His tag)

EFNA5 Origine: Humain Hôte: HEK-293 Cells Recombinant > 92 % by SDS-PAGE. Active
N° du produit ABIN7519951
  • Antigène Voir toutes Ephrin A5 (EFNA5) Protéines
    Ephrin A5 (EFNA5)
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 6
    • 3
    • 2
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Ephrin A5 protéine est marqué à la Fc Tag,His tag.
    Fonction
    Active Recombinant Human Ephrin-A5/EFNA5 Protein
    Séquence
    QDPGSKAVAD RYAVYWNSSN PRFQRGDYHI DVCINDYLDV FCPHYEDSVP EDKTERYVLY MVNFDGYSAC DHTSKGFKRW ECNRPHSPNG PLKFSEKFQL FTPFSLGFEF RPGREYFYIS SAIPDNGRRS CLKLKVFVRP TNSCMKTIGV HDRVFDVNDK VENSLEPADD TVHESAEPSR GEN
    Specificité
    Gln21-Asn203
    Pureté
    > 92 % by SDS-PAGE.
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human EPHA2 at 0.5 μg/mL (100 μL/well) can bind Human EFNA5 with a linear range of 0.02-0.67 ng/mL.
    Top Product
    Discover our top product EFNA5 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Antigène
    Ephrin A5 (EFNA5)
    Autre désignation
    Ephrin-A5/EFNA5 (EFNA5 Produits)
    Synonymes
    EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein
    Sujet

    Description: Ephrin-A5 also known as EFNA5, is a member of the Ephrin family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

    Name: EFNA5,AF1,EFL5,EPLG7,GLC1M,LERK7,RAGS,ephrin-A5

    ID gène
    1946
    UniProt
    P52803
    Pathways
    Signalisation RTK
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