MUC16 Protein (His tag,AVI tag)
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- Antigène Voir toutes MUC16 (CA125) Protéines
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MUC16 protéine est marqué à la His tag,AVI tag.
- Fonction
- Active Recombinant Human MUC-16/CA125 Protein
- Séquence
- GFTHWIPVPT SSTPGTSTVD LGSGTPSSLP SPTTAGPLLV PFTLNFTITN LKYEEDMHCP GSRKFNTTER VLQSLLGPMF KNTSVGPLYS GCRLTLLRSE KDGAATGVDA ICTHRLDPKS PGVDREQLYW ELSQLTNGIK ELGPYTLDRN SLYVNGFTHQ TSAPNTSTPG TSTVDLGTSG TPSSLPSPTS AGPLLVPFTL NFTITNLQYE EDMHHPGSRK FNTTERVLQG LLGPMFKNTS VGLLYSGCRL TLLRPEKNGA ATGM
- Specificité
- Gly12660-Met12923
- Pureté
- > 95 % by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Loaded Human Mesothelin/MSLN Protein, C-hFc&His on ProA Biosensor, can bind Human CA125 Protein, C-His&Avi with an affinity constant of 17.2 nM as determined in BLI assay (Gator).
- Top Product
- Discover our top product CA125 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Antigène
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- Autre désignation
- MUC-16/CA125 (CA125 Produits)
- Synonymes
- CA125 Protein, 1110008I14Rik Protein, Ca125 Protein, Gm1480 Protein, RGD1308422 Protein, MUC16 Protein, mucin 16, cell surface associated Protein, mucin 16 Protein, mucin-16 Protein, MUC16 Protein, Muc16 Protein, LOC476718 Protein, LOC712735 Protein
- Sujet
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Description: The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 Molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
Name: CA125,MUC16,mucin-16
- ID gène
- 94025
- UniProt
- Q8WXI7
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