TYRO3 Protein (Fc Tag,His tag)

N° du produit ABIN7534238

Détail du produit

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TYRO3 protéine est marqué à la Fc Tag,His tag.

Fonction: Active Recombinant Human TYRO3 Protein

Séquence: AGLKLMGAPV KLTVSQGQPV KLNCSVEGME EPDIQWVKDG AVVQNLDQLY IPVSEQHWIG FLSLKSVERS DAGRYWCQVE DGGETEISQP VWLTVEGVPF FTVEPKDLAV PPNAPFQLSC EAVGPPEPVT IVWWRGTTKI GGPAPSPSVL NVTGVTQSTM FSCEAHNLKG LASSRTATVH LQALPAAPFN ITVTKLSSSN ASVAWMPGAD GRALLQSCTV QVTQAPGGWE VLAVVVPVPP FTCLLRDLVP ATNYSLRVRC ANALGPSPYA DWVPFQTKGL APASAPQNLH AIRTDSGLIL EWEEVIPEAP LEGPLGPYKL SWVQDNGTQD ELTVEGTRAN LTGWDPQKDL IVRVCVSNAV GCGPWSQPLV VSSHDRAGQQ GPPHSRTS

Specificité: Ala41-Ser428

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human Gas6 at 2 μg/mL (100 μL/well) can bind Human TYRO3 with a linear range of 0.1-5.6 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Autre désignation: TYRO3 (TYRO3 Produits)

Synonymes: TYRO3 Protein, brt Protein, byk Protein, dtk Protein, rse Protein, sky Protein, tif Protein, Xksy Protein, MGC145734 Protein, DKFZp469I0432 Protein, LOC100231598 Protein, BYK Protein, Dtk Protein, RSE Protein, Sky Protein, Tif Protein, Brt Protein, REK Protein, ksy Protein, xksy Protein, AI323366 Protein, Etk-2 Protein, Rse Protein, TYRO3 protein tyrosine kinase Protein, TYRO3 protein tyrosine kinase L homeolog Protein, TYRO3 protein tyrosine kinase 3 Protein, TYRO3 Protein, tyro3 Protein, Tyro3 Protein, tyro3.L Protein

Sujet:

Description: TYRO3, also known as Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken c-Eyk) constitute a new receptor tyrosine kinase subfamily. TYRO3 protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. TYRO3 has also been identified as a cell entry factor for Ebola and Marburg viruses.

Name: BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif,TYRO3,Dtk,Etk-2,RSE,Rek,Sky,Tif

ID gène: 7301

UniProt: Q06418

Pathways: Signalisation RTK