PSMD10 Protein (AA 1-226)

N° du produit ABIN934994

Détail du produit

Antigène: PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))

Type de proteíne: Recombinant

Attributs du protein: AA 1-226

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Séquence: MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG

Attributs du produit: Purified recombinant Human Gankyrin protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Pureté: > 95 % pure

Information d'application

Indications d'application: Gankyrin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))

Autre désignation: Gankyrin (PSMD10 Produits)

Synonymes: gankyrin Protein, zgc:109707 Protein, dJ889N15.2 Protein, p28 Protein, p28(GANK) Protein, AW554874 Protein, p28Gank Protein, proteasome 26S subunit, non-ATPase 10 Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Protein, psmd10 Protein, PSMD10 Protein, Psmd10 Protein

Sujet: Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. Recombinant human Gankyrin was expressed in E. coli and purified by conventional chromatography techniques.
Alternative Names: Gankyrin protein, 26S proteasome regulatory subunit p28 protein, 26S proteasome non-ATPase regulatory subunit 10 protein, PSMD10., proteasome 26S subunit non ATPase 10 (PSMD10) isoform 1 protein, ankyrin repeat protein p28 protein

Poids moléculaire: 24.4 kDa (226 AA)

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Ubiquitin Proteasome Pathway